Targeted modification of the Per2 clock gene alters circadian function in mPer2(luciferase) (mPer2(Luc)) mice

Modification of the Per2 clock gene in mPer2(Luc) reporter mice significantly alters circadian function. Behavioral period in constant dark is lengthened, and dissociates into two distinct components in constant light. Rhythms exhibit increased bimodality, enhanced phase resetting to light pulses, a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS Comput Biol
मुख्य लेखकों: Ralph, Martin R., Shi, Shu-qun, Johnson, Carl H., Houdek, Pavel, Shrestha, Tenjin C., Crosby, Priya, O’Neill, John S., Sládek, Martin, Stinchcombe, Adam R., Sumová, Alena
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2021
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191895/
https://ncbi.nlm.nih.gov/pubmed/34048425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008987
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