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Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein
The core oscillator generating circadian rhythms in eukaryotes is composed of transcription–translation-based autoregulatory feedback loops in which clock gene products negatively affect their own expression. A key step in this mechanism involves the periodic nuclear accumulation of clock proteins f...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125916/ https://ncbi.nlm.nih.gov/pubmed/11889036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.6.1301 |
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