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Loss of circadian rhythmicity in aging mPer1(-/-) mCry2(-/-) mutant mice
The mPer1, mPer2, mCry1, and mCry2 genes play a central role in the molecular mechanism driving the central pacemaker of the mammalian circadian clock, located in the suprachiasmatic nuclei (SCN) of the hypothalamus. In vitro studies suggest a close interaction of all mPER and mCRY proteins. We inve...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196069/ https://ncbi.nlm.nih.gov/pubmed/12782655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.256103 |
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