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Dimerization and nuclear entry of mPER proteins in mammalian cells

Nuclear entry of circadian oscillatory gene products is a key step for the generation of a 24-hr cycle of the biological clock. We have examined nuclear import of clock proteins of the mammalian period gene family and the effect of serum shock, which induces a synchronous clock in cultured cells. Pr...

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Detalhes bibliográficos
Main Authors: Yagita, Kazuhiro, Yamaguchi, Shun, Tamanini, Filippo, van der Horst, Gijsbertus T.J., Hoeijmakers, Jan H.J., Yasui, Akira, Loros, Jennifer J., Dunlap, Jay C., Okamura, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316664/
https://ncbi.nlm.nih.gov/pubmed/10837028
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