Cytoplasmic Thioredoxin Reductase Is Essential for Embryogenesis but Dispensable for Cardiac Development

Two distinct thioredoxin/thioredoxin reductase systems are present in the cytosol and the mitochondria of mammalian cells. Thioredoxins (Txn), the main substrates of thioredoxin reductases (Txnrd), are involved in numerous physiological processes, including cell-cell communication, redox metabolism,...

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Autors principals: Jakupoglu, Cemile, Przemeck, Gerhard K. H., Schneider, Manuela, Moreno, Stéphanie G., Mayr, Nadja, Hatzopoulos, Antonis K., de Angelis, Martin Hrabé, Wurst, Wolfgang, Bornkamm, Georg W., Brielmeier, Markus, Conrad, Marcus
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC549365/
https://ncbi.nlm.nih.gov/pubmed/15713651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.1980-1988.2005
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