Cytoplasmic Thioredoxin Reductase Is Essential for Embryogenesis but Dispensable for Cardiac Development

Two distinct thioredoxin/thioredoxin reductase systems are present in the cytosol and the mitochondria of mammalian cells. Thioredoxins (Txn), the main substrates of thioredoxin reductases (Txnrd), are involved in numerous physiological processes, including cell-cell communication, redox metabolism,...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Jakupoglu, Cemile, Przemeck, Gerhard K. H., Schneider, Manuela, Moreno, Stéphanie G., Mayr, Nadja, Hatzopoulos, Antonis K., de Angelis, Martin Hrabé, Wurst, Wolfgang, Bornkamm, Georg W., Brielmeier, Markus, Conrad, Marcus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2005
Soggetti:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549365/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15713651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.5.1980-1988.2005
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