Cytoplasmic Thioredoxin Reductase Is Essential for Embryogenesis but Dispensable for Cardiac Development

Two distinct thioredoxin/thioredoxin reductase systems are present in the cytosol and the mitochondria of mammalian cells. Thioredoxins (Txn), the main substrates of thioredoxin reductases (Txnrd), are involved in numerous physiological processes, including cell-cell communication, redox metabolism,...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Jakupoglu, Cemile, Przemeck, Gerhard K. H., Schneider, Manuela, Moreno, Stéphanie G., Mayr, Nadja, Hatzopoulos, Antonis K., de Angelis, Martin Hrabé, Wurst, Wolfgang, Bornkamm, Georg W., Brielmeier, Markus, Conrad, Marcus
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2005
Onderwerpen:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549365/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15713651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.5.1980-1988.2005
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