Cytoplasmic Thioredoxin Reductase Is Essential for Embryogenesis but Dispensable for Cardiac Development

Two distinct thioredoxin/thioredoxin reductase systems are present in the cytosol and the mitochondria of mammalian cells. Thioredoxins (Txn), the main substrates of thioredoxin reductases (Txnrd), are involved in numerous physiological processes, including cell-cell communication, redox metabolism,...

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Detalhes bibliográficos
Main Authors: Jakupoglu, Cemile, Przemeck, Gerhard K. H., Schneider, Manuela, Moreno, Stéphanie G., Mayr, Nadja, Hatzopoulos, Antonis K., de Angelis, Martin Hrabé, Wurst, Wolfgang, Bornkamm, Georg W., Brielmeier, Markus, Conrad, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549365/
https://ncbi.nlm.nih.gov/pubmed/15713651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.1980-1988.2005
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