Cytoplasmic Thioredoxin Reductase Is Essential for Embryogenesis but Dispensable for Cardiac Development

Two distinct thioredoxin/thioredoxin reductase systems are present in the cytosol and the mitochondria of mammalian cells. Thioredoxins (Txn), the main substrates of thioredoxin reductases (Txnrd), are involved in numerous physiological processes, including cell-cell communication, redox metabolism,...

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Главные авторы: Jakupoglu, Cemile, Przemeck, Gerhard K. H., Schneider, Manuela, Moreno, Stéphanie G., Mayr, Nadja, Hatzopoulos, Antonis K., de Angelis, Martin Hrabé, Wurst, Wolfgang, Bornkamm, Georg W., Brielmeier, Markus, Conrad, Marcus
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
Предметы:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC549365/
https://ncbi.nlm.nih.gov/pubmed/15713651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.1980-1988.2005
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