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Uncoupling of Oxidative Stress Resistance and Lifespan in Long-lived isp-1 Mitochondrial Mutants in Caenorhabditis elegans

Mutations affecting components of the mitochondrial electron transport chain have been shown to increase lifespan in multiple species including the worm Caenorhabditis elegans. While it was originally proposed that decreased generation of reactive oxygen species (ROS) resulting from lower rates of e...

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Библиографические подробности
Опубликовано в: :Free Radic Biol Med
Главные авторы: Dues, Dylan J., Schaar, Claire E., Johnson, Benjamin K., Bowman, Megan J., Winn, Mary E., Senchuk, Megan M., Van Raamsdonk, Jeremy M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493208/
https://ncbi.nlm.nih.gov/pubmed/28392283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.04.004
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