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Uncoupling of Oxidative Stress Resistance and Lifespan in Long-lived isp-1 Mitochondrial Mutants in Caenorhabditis elegans

Mutations affecting components of the mitochondrial electron transport chain have been shown to increase lifespan in multiple species including the worm Caenorhabditis elegans. While it was originally proposed that decreased generation of reactive oxygen species (ROS) resulting from lower rates of e...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Dues, Dylan J., Schaar, Claire E., Johnson, Benjamin K., Bowman, Megan J., Winn, Mary E., Senchuk, Megan M., Van Raamsdonk, Jeremy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493208/
https://ncbi.nlm.nih.gov/pubmed/28392283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.04.004
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