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Protein Structure Determination using Metagenome sequence data
Despite decades of work by structural biologists, there are still ~5200 protein families with unknown structure outside the range of comparative modeling. We show that Rosetta structure prediction guided by residue-residue contacts inferred from evolutionary information can accurately model proteins...
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| Izdano u: | Science |
|---|---|
| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5493203/ https://ncbi.nlm.nih.gov/pubmed/28104891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aah4043 |
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