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Clonal evolution of pre-leukemic hematopoietic stem cells in acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive blood cancer that results from an abnormal expansion of uncontrollably proliferating myeloid progenitors that have lost the capacity to differentiate. AML encompasses many genetically distinct sub-types that predominantly develop de novo. However, AML ca...

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Bibliografische gegevens
Gepubliceerd in:Exp Hematol
Hoofdauteurs: Sykes, Stephen M., Kokkaliaris, Konstantinos D., Milsom, Michael D., Levine, Ross L., Majeti, Ravindra
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492948/
https://ncbi.nlm.nih.gov/pubmed/26455528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.08.012
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