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Clonal evolution of pre-leukemic hematopoietic stem cells in acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive blood cancer that results from an abnormal expansion of uncontrollably proliferating myeloid progenitors that have lost the capacity to differentiate. AML encompasses many genetically distinct sub-types that predominantly develop de novo. However, AML ca...

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Detalles Bibliográficos
Publicado en:Exp Hematol
Autores principales: Sykes, Stephen M., Kokkaliaris, Konstantinos D., Milsom, Michael D., Levine, Ross L., Majeti, Ravindra
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492948/
https://ncbi.nlm.nih.gov/pubmed/26455528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.08.012
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