Clonal evolution of pre-leukemic hematopoietic stem cells in acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive blood cancer that results from an abnormal expansion of uncontrollably proliferating myeloid progenitors that have lost the capacity to differentiate. AML encompasses many genetically distinct sub-types that predominantly develop de novo. However, AML ca...

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Vydáno v:Exp Hematol
Hlavní autoři: Sykes, Stephen M., Kokkaliaris, Konstantinos D., Milsom, Michael D., Levine, Ross L., Majeti, Ravindra
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492948/
https://ncbi.nlm.nih.gov/pubmed/26455528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.08.012
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