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Single-Dose Pharmacokinetics and Metabolism of [(14)C]Remofovir in Rats and Cynomolgus Monkeys
Single-dose pharmacokinetics and metabolism of [(14)C]remofovir was studied in rats and monkeys following intravenous (i.v.) and oral administration (30 mg/kg of body weight). Oral absorption and bioavailability were 29.7 and 5.42% in rats and 65.6 and 19.4% in monkeys, respectively. Following i.v....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549278/ https://ncbi.nlm.nih.gov/pubmed/15728885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.3.925-930.2005 |
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