Disposition and Metabolic Profiles of [(14)C]Viramidine and [(14)C]Ribavirin in Rat and Monkey Red Blood Cells and Liver

The disposition and metabolic profiles of [(14)C]viramidine and [(14)C]ribavirin were compared in rat and monkey red blood cells and liver. Our data reveal that the total ribavirin-related components (ribavirin plus its mono-, di-, and triphosphate metabolites) may account for most of the drug in mo...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Lin, Chin-Chung, Lourenco, David, Xu, Guifen, Yeh, Li-Tain
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400578/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15105147/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.5.1872-1875.2004
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