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Disposition and Metabolic Profiles of [(14)C]Viramidine and [(14)C]Ribavirin in Rat and Monkey Red Blood Cells and Liver

The disposition and metabolic profiles of [(14)C]viramidine and [(14)C]ribavirin were compared in rat and monkey red blood cells and liver. Our data reveal that the total ribavirin-related components (ribavirin plus its mono-, di-, and triphosphate metabolites) may account for most of the drug in mo...

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Detalhes bibliográficos
Main Authors: Lin, Chin-Chung, Lourenco, David, Xu, Guifen, Yeh, Li-Tain
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400578/
https://ncbi.nlm.nih.gov/pubmed/15105147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1872-1875.2004
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