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Pharmacokinetics of AT-2266 Administered Orally to Mice, Rats, Dogs, and Monkeys

The pharmacokinetics of AT-2266 (1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine- 3-carboxylic acid) were studied in various experimental animals and compared in a number of aspects with those of norfloxacin. Both agents were administered orally. The mean peak plasma levels of...

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Bibliographic Details
Main Authors: Nakamura, Shinichi, Kurobe, Nobuyuki, Kashimoto, Shigeki, Ohue, Tomio, Takase, Yoshiyuki, Shimizu, Masanao
Format: Artigo
Language:Inglês
Published: 1983
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC185104/
https://ncbi.nlm.nih.gov/pubmed/6226241
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