Pharmacokinetics of AT-2266 Administered Orally to Mice, Rats, Dogs, and Monkeys

The pharmacokinetics of AT-2266 (1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine- 3-carboxylic acid) were studied in various experimental animals and compared in a number of aspects with those of norfloxacin. Both agents were administered orally. The mean peak plasma levels of...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Nakamura, Shinichi, Kurobe, Nobuyuki, Kashimoto, Shigeki, Ohue, Tomio, Takase, Yoshiyuki, Shimizu, Masanao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1983
Schlagworte:	Pharmacology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185104/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6226241/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.1.54
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