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Pharmacokinetics and Metabolism of [(14)C]Ribavirin in Rats and Cynomolgus Monkeys
Absorption, pharmacokinetics, distribution, metabolism, and excretion of [(14)C]ribavirin were studied in rats (30 mg/kg of body weight) and cynomolgus monkeys (10 mg/kg) after intravenous (i.v.) and oral administration. The oral absorption and bioavailability were 83 and 59%, respectively, in rats...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152481/ https://ncbi.nlm.nih.gov/pubmed/12654676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.4.1395-1398.2003 |
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