Efficacy and Toxicity of Zinc Salts as Candidate Topical Microbicides against Vaginal Herpes Simplex Virus Type 2 Infection

Zinc salt solutions administered as topical microbicides provided significant protection against herpes simplex virus type 2 infection in a mouse vaginal challenge model. However, at the therapeutic concentration, the salt solutions caused sloughing of sheets of vaginal epithelial cells. These obser...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Bourne, Nigel, Stegall, Rachael, Montano, Raquel, Meador, Michael, Stanberry, Lawrence R., Milligan, Gregg N.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2005
Assuntos:	Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549274/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15728922/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.3.1181-1183.2005
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!