Flavoenzyme-mediated reduction reactions and antitumor activity of nitrogen-containing tetracyclic ortho-quinone compounds and their nitrated derivatives

Nitrogen-based tetracyclic ortho-quinones (naphtho[1'2':4.5]imidazo[1,2-a]pyridine-5,6-diones, NPDOs) and their nitro-substituted derivatives (nitro-(P)NPDOs) were obtained by condensation of substituted 2,3-dichloro-1,4-naphthoquinones with 2-amino-pyridine and -pyrimidine and nitration a...

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Vydáno v:EXCLI J
Hlavní autoři: Peciukaityte-Alksne, Milda, Šarlauskas, Jonas, Miseviciene, Lina, Maroziene, Audrone, Cenas, Narimantas, Krikštopaitis, Kastis, Staniulyte, Zita, Anusevicius, Žilvinas
Médium: Artigo
Jazyk:Inglês
Vydáno: Leibniz Research Centre for Working Environment and Human Factors 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491926/
https://ncbi.nlm.nih.gov/pubmed/28694766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2017-273
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