The Study of NADPH-Dependent Flavoenzyme-Catalyzed Reduction of Benzo[1,2-c]1,2,5-oxadiazole N-Oxides (Benzofuroxans)

The enzymatic reactivity of a series of benzo[1,2-c]1,2,5-oxadiazole N-oxides (benzofuroxans; BFXs) towards mammalian single-electron transferring NADPH:cytochrome P-450 reductase (P-450R) and two-electron (hydride) transferring NAD(P)H:quinone oxidoreductase (NQO1) was examined in this work. Since...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Šarlauskas, Jonas, Misevičienė, Lina, Marozienė, Audronė, Karvelis, Laimonas, Stankevičiūtė, Jonita, Krikštopaitis, Kastis, Čėnas, Narimantas, Yantsevich, Aleksey, Laurynėnas, Audrius, Anusevičius, Žilvinas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284768/
https://ncbi.nlm.nih.gov/pubmed/25517035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms151223307
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