No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice

Base excision repair (BER) is a major pathway for removal of DNA base lesions and maintenance of genomic stability, which is essential in cancer prevention. DNA glycosylases recognize and remove specific lesions in the first step of BER. The existence of a number of these enzymes with overlapping su...

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Foilsithe in:Sci Rep
Main Authors: Rolseth, Veslemøy, Luna, Luisa, Olsen, Ann Karin, Suganthan, Rajikala, Scheffler, Katja, Neurauter, Christine G., Esbensen, Ying, Kuśnierczyk, Anna, Hildrestrand, Gunn A., Graupner, Anne, Andersen, Jill M., Slupphaug, Geir, Klungland, Arne, Nilsen, Hilde, Bjørås, Magnar
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491499/
https://ncbi.nlm.nih.gov/pubmed/28663564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04472-4
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