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Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA

The mild phenotype associated with targeted disruption of the mouse OGG1 and NTH1 genes has been attributed to the existence of back-up activities and/or alternative pathways for the removal of oxidised DNA bases. We have characterised two new genes in human cells that encode DNA glycosylases, homol...

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Detalhes bibliográficos
Main Authors: Morland, Ingrid, Rolseth, Veslemøy, Luna, Luisa, Rognes, Torbjørn, Bjørås, Magnar, Seeberg, Erling
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137166/
https://ncbi.nlm.nih.gov/pubmed/12433996
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