Escherichia coli Nth and human hNTH1 DNA glycosylases are involved in removal of 8-oxoguanine from 8-oxoguanine/guanine mispairs in DNA

The spectrum of DNA damage caused by reactive oxygen species includes a wide variety of modifications of purine and pyrimidine bases. Among these modified bases, 7,8-dihydro-8-oxoguanine (8-oxoG) is an important mutagenic lesion. Base excision repair is a critical mechanism for preventing mutations...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Matsumoto, Yukiko, Zhang, Qiu-Mei, Takao, Masashi, Yasui, Akira, Yonei, Shuji
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37258/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11328882/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.9.1975
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