No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice

Base excision repair (BER) is a major pathway for removal of DNA base lesions and maintenance of genomic stability, which is essential in cancer prevention. DNA glycosylases recognize and remove specific lesions in the first step of BER. The existence of a number of these enzymes with overlapping su...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Rolseth, Veslemøy, Luna, Luisa, Olsen, Ann Karin, Suganthan, Rajikala, Scheffler, Katja, Neurauter, Christine G., Esbensen, Ying, Kuśnierczyk, Anna, Hildrestrand, Gunn A., Graupner, Anne, Andersen, Jill M., Slupphaug, Geir, Klungland, Arne, Nilsen, Hilde, Bjørås, Magnar
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491499/
https://ncbi.nlm.nih.gov/pubmed/28663564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04472-4
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