No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice

Base excision repair (BER) is a major pathway for removal of DNA base lesions and maintenance of genomic stability, which is essential in cancer prevention. DNA glycosylases recognize and remove specific lesions in the first step of BER. The existence of a number of these enzymes with overlapping su...

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Vydáno v:Sci Rep
Hlavní autoři: Rolseth, Veslemøy, Luna, Luisa, Olsen, Ann Karin, Suganthan, Rajikala, Scheffler, Katja, Neurauter, Christine G., Esbensen, Ying, Kuśnierczyk, Anna, Hildrestrand, Gunn A., Graupner, Anne, Andersen, Jill M., Slupphaug, Geir, Klungland, Arne, Nilsen, Hilde, Bjørås, Magnar
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491499/
https://ncbi.nlm.nih.gov/pubmed/28663564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04472-4
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