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BKM120 induces apoptosis and inhibits tumor growth in medulloblastoma

Medulloblastoma (MB) is the most common malignant brain tumor in children, accounting for nearly 20 percent of all childhood brain tumors. New treatment strategies are needed to improve patient survival outcomes and to reduce adverse effects of current therapy. The phosphatidylinositol-3-kinase (PI3...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhao, Ping, Hall, Jacob, Durston, Mary, Voydanoff, Austin, VanSickle, Elizabeth, Kelly, Shannon, Nagulapally, Abhinav B, Bond, Jeffery, Saulnier Sholler, Giselle
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491106/
https://ncbi.nlm.nih.gov/pubmed/28662162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179948
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