Specific gene expression signatures induced by the multiple oncogenic alterations that occur within the PTEN/PI3K/AKT pathway in lung cancer

Hyperactivation of the phosphatydil-inositol-3' phosphate kinase (PI3K)/AKT pathway is observed in most NSCLCs, promoting proliferation, migration, invasion and resistance to therapy. AKT can be activated through several mechanisms that include loss of the negative regulator PTEN, activating mu...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: De Marco, Carmela, Laudanna, Carmelo, Rinaldo, Nicola, Oliveira, Duarte Mendes, Ravo, Maria, Weisz, Alessandro, Ceccarelli, Michele, Caira, Elvira, Rizzuto, Antonia, Zoppoli, Pietro, Malanga, Donatella, Viglietto, Giuseppe
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2017
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491004/
https://ncbi.nlm.nih.gov/pubmed/28662101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178865
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