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The Role of Somatic L1 Retrotransposition in Human Cancers
The human LINE-1 (or L1) element is a non-LTR retrotransposon that is mobilized through an RNA intermediate by an L1-encoded reverse transcriptase and other L1-encoded proteins. L1 elements remain actively mobile today and continue to mutagenize human genomes. Importantly, when new insertions disrup...
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| Опубликовано в: : | Viruses |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5490808/ https://ncbi.nlm.nih.gov/pubmed/28561751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9060131 |
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