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Landscape of Somatic Retrotransposition in Human Cancers
Transposable elements (TEs) are abundant in the human genome, and some are capable of generating new insertions through RNA intermediates. In cancer, the disruption of cellular mechanisms that normally suppress TE activity may facilitate mutagenic retrotranspositions. We performed single-nucleotide...
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| Hauptverfasser: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3656569/ https://ncbi.nlm.nih.gov/pubmed/22745252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1222077 |
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