Analysis of variable retroduplications in human populations suggests coupling of retrotransposition to cell division

In primates and other animals, reverse transcription of mRNA followed by genomic integration creates retroduplications. Expressed retroduplications are either “retrogenes” coding for functioning proteins, or expressed “processed pseudogenes,” which can function as noncoding RNAs. To date, little is...

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Detalhes bibliográficos
Main Authors: Abyzov, Alexej, Iskow, Rebecca, Gokcumen, Omer, Radke, David W., Balasubramanian, Suganthi, Pei, Baikang, Habegger, Lukas, Lee, Charles, Gerstein, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847774/
https://ncbi.nlm.nih.gov/pubmed/24026178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.154625.113
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