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The Role of Somatic L1 Retrotransposition in Human Cancers

The human LINE-1 (or L1) element is a non-LTR retrotransposon that is mobilized through an RNA intermediate by an L1-encoded reverse transcriptase and other L1-encoded proteins. L1 elements remain actively mobile today and continue to mutagenize human genomes. Importantly, when new insertions disrup...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Viruses
Päätekijät: Scott, Emma C., Devine, Scott E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490808/
https://ncbi.nlm.nih.gov/pubmed/28561751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9060131
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