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KSR as a therapeutic target for Ras-dependent cancers

INTRODUCTION: Targeting downstream effectors required for oncogenic Ras signaling is a potential alternative or complement to the development of more direct approaches targeting Ras in the treatment of Ras-dependent cancers. AREAS COVERED: Here we review literature pertaining to the molecular scaffo...

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Publicat a:Expert Opin Ther Targets
Autors principals: Neilsen, Beth K., Frodyma, Danielle E., Lewis, Robert E., Fisher, Kurt W.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490495/
https://ncbi.nlm.nih.gov/pubmed/28333549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2017.1311325
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