Targeting MCL-1 sensitizes human esophageal squamous cell carcinoma cells to cisplatin-induced apoptosis

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies in China and is an exceptionally drug-resistant tumor with a 5-year survival rate less than 15%. Cisplatin is the most commonly used conventional chemotherapeutic drug for the treatment of ESCC, but some pat...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Yu, Xinfang, Li, Wei, Xia, Zhenkun, Xie, Li, Ma, Xiaolong, Liang, Qi, Liu, Lijun, Wang, Jian, Zhou, Xinmin, Yang, Yifeng, Liu, Haidan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490225/
https://ncbi.nlm.nih.gov/pubmed/28659182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3442-y
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