EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis

Polycomb group (PcG) proteins are highly conserved epigenetic effectors that maintain the silenced state of genes. EZH2 is the catalytic core and one of the most important components of the polycomb repressive complex 2 (PRC2). In non-small cell lung cancer (NSCLC) cells and primary lung tumors, we...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Haidan, Li, Wei, Yu, Xinfang, Gao, Feng, Duan, Zhi, Ma, Xiaolong, Tan, Shiming, Yuan, Yunchang, Liu, Lijun, Wang, Jian, Zhou, Xinmin, Yang, Yifeng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302918/
https://ncbi.nlm.nih.gov/pubmed/27472460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10841
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