Treatment of metastatic uveal melanoma with adoptive transfer of tumor infiltrating lymphocytes: a single-center phase 2 study

BACKGROUND: Uveal melanoma is a rare tumor with no established treatments once metastases develop. Although a variety of immune based therapies have demonstrated efficacy in metastatic cutaneous melanoma, their use in ocular variants has been disappointing. Recently, adoptive T cell therapy has show...

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Udgivet i:Lancet Oncol
Main Authors: Chandran, Smita S., Somerville, Robert P.T., Yang, James C., Sherry, Richard M., Klebanoff, Christopher A., Goff, Stephanie L., Wunderlich, John R., Danforth, David N., Zlott, Daniel, Paria, Biman C., Sabesan, Arvind C., Srivastava, Abhishek K., Xi, Liqiang, Pham, Trinh H., Raffeld, Mark, White, Donald E., Toomey, Mary Ann, Rosenberg, Steven A., Kammula, Udai S.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490083/
https://ncbi.nlm.nih.gov/pubmed/28395880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(17)30251-6
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