Tumor-specific effector CD8+ T cells that can establish immunological memory in humans after adoptive transfer are marked by expression of IL-7 receptor and c-myc

The optimal T cell attributes for adoptive cancer immunotherapy are unclear. Recent clinical trials of ex vivo expanded tumor-infiltrating lymphocytes indicated that differentiated T effector cells can elicit durable anti-tumor responses in some cancer patients, with their anti-tumor activity tightl...

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Vydáno v:Cancer Res
Hlavní autoři: Chandran, Smita S., Paria, Biman C., Srivastava, Abhishek K., Rothermel, Luke D., Stephens, Daniel J., Kammula, Udai S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537826/
https://ncbi.nlm.nih.gov/pubmed/26100671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0584
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