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The Stoichiometric Production of IL-2 and IFN-γ mRNA Defines Memory T Cells That Can Self-Renew After Adoptive Transfer in Humans

Adoptive immunotherapy using ex vivo–expanded tumor-reactive lymphocytes can mediate durable cancer regression in selected melanoma patients. Analyses of these trials have associated the in vivo engraftment ability of the transferred cells with their antitumor efficacy. Thus, there is intensive clin...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Transl Med
Main Authors: Wang, Anran, Chandran, Smita, Shah, Syed A., Chiu, Yu, Paria, Biman C., Aghamolla, Tamara, Alvarez-Downing, Melissa M., Lee, Chyi-Chia Richard, Singh, Sanmeet, Li, Thomas, Dudley, Mark E., Restifo, Nicholas P., Rosenberg, Steven A., Kammula, Udai S.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453124/
https://ncbi.nlm.nih.gov/pubmed/22932225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3004306
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