A soluble mouse brain splice variant of type 2α corticotropin-releasing factor (CRF) receptor binds ligands and modulates their activity

Peptides of the corticotropin-releasing factor (CRF) family signal through the activation of two receptors, CRF receptor type 1 (CRFR1) and type 2 (CRFR2), both of which exist as multiple splice variants. We have identified a cDNA from mouse brain encoding a splice variant, soluble CRFR2α (sCRFR2α),...

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Main Authors: Chen, Alon M., Perrin, Marilyn H., DiGruccio, Michael R., Vaughan, Joan M., Brar, Bhawanjit K., Arias, Carlos M., Lewis, Kathy A., Rivier, Jean E., Sawchenko, Paul E., Vale, Wylie W.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2005
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC549000/
https://ncbi.nlm.nih.gov/pubmed/15701705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409583102
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