Characterization of Multisubstituted Corticotropin Releasing Factor (CRF) Peptide Antagonists (Astressins)

CRF mediates numerous stress-related endocrine, autonomic, metabolic, and behavioral responses. We present the synthesis and chemical and biological properties of astressin B analogues {cyclo(30–33)[D-Phe(12),Nle(21,38),C(α)MeLeu(27,40),Glu(30),Lys(33)]-acetyl-h/r-CRF((9–41))}. Out of 37 novel pepti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Erchegyi, Judit, Wang, Lixin, Gulyas, Jozsef, Samant, Manoj, Perrin, Marilyn H., Lewis, Kathy, Miller, Charleen, Vaughan, Joan, Donaldson, Cynthia, Fischer, Wolfgang, Low, William, Yakabi, Seiichi, Karasawa, Hiroshi, Taché, Yvette, Rivier, Catherine, Rivier, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959268/
https://ncbi.nlm.nih.gov/pubmed/26789203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b00926
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados