Stressin(1)-A, a Potent Corticotropin Releasing Factor Receptor 1 (CRF(1))-Selective Peptide Agonist

The potencies and selectivity of peptide CRF antagonists is increased through structural constraints suggesting that the resulting ligands assume distinct conformations when interacting with CRF(1) and CRF(2) receptors. To develop selective CRF receptor agonists, we have scanned the sequence -Gln-Al...

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Detalhes bibliográficos
Main Authors: Rivier, Jean, Gulyas, Jozsef, Kunitake, Koichi, DiGruccio, Michael, Cantle, Jeffrey P., Perrin, Marilyn H., Donaldson, Cindy, Vaughan, Joan, Million, Mulugeta, Gourcerol, Guillaume, Adelson, David W., Rivier, Catherine, Taché, Yvette, Vale, Wylie
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593142/
https://ncbi.nlm.nih.gov/pubmed/17335188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0613875
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