Stressin(1)-A, a Potent Corticotropin Releasing Factor Receptor 1 (CRF(1))-Selective Peptide Agonist

The potencies and selectivity of peptide CRF antagonists is increased through structural constraints suggesting that the resulting ligands assume distinct conformations when interacting with CRF(1) and CRF(2) receptors. To develop selective CRF receptor agonists, we have scanned the sequence -Gln-Al...

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Détails bibliographiques
Auteurs principaux: Rivier, Jean, Gulyas, Jozsef, Kunitake, Koichi, DiGruccio, Michael, Cantle, Jeffrey P., Perrin, Marilyn H., Donaldson, Cindy, Vaughan, Joan, Million, Mulugeta, Gourcerol, Guillaume, Adelson, David W., Rivier, Catherine, Taché, Yvette, Vale, Wylie
Format: Artigo
Langue:Inglês
Publié: 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593142/
https://ncbi.nlm.nih.gov/pubmed/17335188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0613875
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