Stressin(1)-A, a Potent Corticotropin Releasing Factor Receptor 1 (CRF(1))-Selective Peptide Agonist

The potencies and selectivity of peptide CRF antagonists is increased through structural constraints suggesting that the resulting ligands assume distinct conformations when interacting with CRF(1) and CRF(2) receptors. To develop selective CRF receptor agonists, we have scanned the sequence -Gln-Al...

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Autors principals: Rivier, Jean, Gulyas, Jozsef, Kunitake, Koichi, DiGruccio, Michael, Cantle, Jeffrey P., Perrin, Marilyn H., Donaldson, Cindy, Vaughan, Joan, Million, Mulugeta, Gourcerol, Guillaume, Adelson, David W., Rivier, Catherine, Taché, Yvette, Vale, Wylie
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593142/
https://ncbi.nlm.nih.gov/pubmed/17335188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0613875
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