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Cortagine, a CRF(1) agonist, induces stresslike alterations of colonic function and visceral hypersensitivity in rodents primarily through peripheral pathways
Corticotropin-releasing factor (CRF) 1 receptor (CRF(1)) activation in the brain is a core pathway orchestrating the stress response. Anatomical data also support the existence of CRF signaling components within the colon. We investigated the colonic response to intraperitoneal (ip) injection of cor...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Physiological Society
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711753/ https://ncbi.nlm.nih.gov/pubmed/19407218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00072.2009 |
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