Cortagine, a CRF(1) agonist, induces stresslike alterations of colonic function and visceral hypersensitivity in rodents primarily through peripheral pathways

Corticotropin-releasing factor (CRF) 1 receptor (CRF(1)) activation in the brain is a core pathway orchestrating the stress response. Anatomical data also support the existence of CRF signaling components within the colon. We investigated the colonic response to intraperitoneal (ip) injection of cor...

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Autors principals: Larauche, Muriel, Gourcerol, Guillaume, Wang, Lixin, Pambukchian, Karina, Brunnhuber, Stefan, Adelson, David W., Rivier, Jean, Million, Mulugeta, Taché, Yvette
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2009
Matèries:
Hormones and Signaling
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711753/
https://ncbi.nlm.nih.gov/pubmed/19407218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00072.2009
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