A Tunable Brake for HECT Ubiquitin Ligases

The HECT E3 ligases ubiquitinate numerous transcription factors and signaling molecules and their activity must be tightly controlled to prevent cancer, immune disorders, and other diseases. In this study we have found unexpectedly that peptide linkers tethering WW domains in several HECT family mem...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Chen, Zan, Jiang, Hanjie, Xu, Wei, Li, Xiaoguang, Dempsey, Daniel R., Zhang, Xiangbin, Devreotes, Peter, Wolberger, Cynthia, Amzel, Mario, Gabelli, Sandra, Cole, Philip A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489419/
https://ncbi.nlm.nih.gov/pubmed/28475870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.03.020
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