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Targeting Notch-activated M1 Macrophages Attenuates Joint Tissue Damage in A Mouse Model of Inflammatory Arthritis
Expression of Notch signaling molecules are increased in synovium from patients with rheumatoid arthritis (RA). However, it is not known which cell type(s) in RA synovium have Notch activation or if they play a pathogenetic role in RA. Here, we used Hes1-GFP/TNF-transgenic (TNF-Tg) mice to investiga...
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| Pubblicato in: | J Bone Miner Res |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5489377/ https://ncbi.nlm.nih.gov/pubmed/28256007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3117 |
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