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VEGF-C attenuates joint damage in chronic inflammatory arthritis by accelerating local lymphatic drainage

OBJECTIVE: To investigate if enhancement of joint lymphangiogenesis by injecting VEGF-C adeno-associated virus (AAV) into joints has therapeutic efficacy in chronic inflammatory arthritis in mice. METHODS: TNF transgenic (TNF-Tg) mice were used as a model of chronic inflammatory arthritis. Human VEG...

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Detalhes bibliográficos
Main Authors: Zhou, Quan, Guo, Ruolin, Wood, Ronald, Boyce, Brendan F., Liang, Qianqian, Wang, Yong-Jun, Schwarz, Edward M., Xing, Lianping
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149728/
https://ncbi.nlm.nih.gov/pubmed/21538325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30421
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