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Inhibition of lymphangiogenesis and lymphatic drainage via VEGFR-3 blockade increases the severity of inflammation in chronic inflammatory arthritis

OBJECT: Investigation of the effect of lymphatic inhibition on joint and draining lymph node pathology during the course of arthritis progression in mice. METHOD: TNF transgenic (TNF-Tg) mice were used as a model of chronic inflammatory arthritis. Mice received contrast enhanced MRI to obtain ankle...

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Détails bibliographiques
Auteurs principaux: Guo, Ruolin, Zhou, Quan, Proulx, Steven T., Wood, Ronald, Ji, Rui-Cheng, Ritchlin, Christopher T., Pytowski, Bronislaw, Zhu, Zhenping, Wang, Yong-Jun, Schwarz, Edward M., Xing, Lianping
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810533/
https://ncbi.nlm.nih.gov/pubmed/19714652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24764
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