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The Tiam1 PDZ Domain Couples to Syndecan1 and Promotes Cell-Matrix Adhesion
The T-cell lymphoma invasion and metastasis gene 1 (Tiam1) is a guanine exchange factor (GEF) for the Rho-family GTPase Rac1 that is crucial for the integrity of adherens junctions, tight junctions, and cell-matrix interactions. This GEF contains several protein-protein interaction domains, includin...
Gardado en:
| Publicado en: | J Mol Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5489123/ https://ncbi.nlm.nih.gov/pubmed/20361982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.047 |
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