The Tiam1 PDZ Domain Couples to Syndecan1 and Promotes Cell-Matrix Adhesion

The T-cell lymphoma invasion and metastasis gene 1 (Tiam1) is a guanine exchange factor (GEF) for the Rho-family GTPase Rac1 that is crucial for the integrity of adherens junctions, tight junctions, and cell-matrix interactions. This GEF contains several protein-protein interaction domains, includin...

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Foilsithe in:J Mol Biol
Main Authors: Shepherd, Tyson R., Klaus, Suzi M., Liu, Xu, Ramaswamy, S., DeMali, Kris A., Fuentes, Ernesto J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489123/
https://ncbi.nlm.nih.gov/pubmed/20361982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.047
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