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Histamine modulation of the basal ganglia circuitry in the development of pathological grooming
Aberrant histaminergic function has been proposed as a cause of tic disorders. A rare mutation in the enzyme that produces histamine (HA), histidine decarboxylase (HDC), has been identified in patients with Tourette syndrome (TS). Hdc knockout mice exhibit repetitive behavioral pathology and neuroch...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5488951/ https://ncbi.nlm.nih.gov/pubmed/28584117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704547114 |
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